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Hansten and Horn describe three types of actions- a. considering alternative drugs that may be less likely to interact and thus avoiding the interaction b. circumventing the interaction by minimizing the consequence of the interaction and c. monitoring the patient to detect the consequence of the interaction and minimizing the adverse outcome.
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Different possibilities account for the sex-specific differences: first, the differences in the recombination patterns between male and female meiosis; second, more permissive checkpoints in females than males; third, the age-related loss of chromosome cohesion in female gametes; and fourth, the difference in the ability to detect the consequences of meiotic division errors [5], [11] [15], [34].
The computer simulations shown in Figure 4 are limited to measure the power of the considered procedures to detect the consequences of changes in matrix orientation and shape.
Such intra-annual data make it possible to detect the consequences of short-term environmental signals on tree-ring formation and radial growth.
Finally, follow-up tests with offspring to HCMV IgM-positive mothers are essential, in order to detect the consequences of congenital infection and to allow treatment to occur as early as possible.
We investigated the link between cooperative behavior and dispersal in experimental microcosms of a unicellular ciliate, Tetrahymena thermophila, to understand the potential and nature of trade-offs between these traits and to detect the consequences of this relationship on other life history characteristics.
She has been consulted, she has advised and warned, but few have detected the consequence.
PICT is measured by a functional test that detects the consequences of selection pressures.
As the risk of tuberculosis progression is high in very young children (<3 years), should the disease have not been detected the consequences may have been severe [ 14].
Either there is interesting biology that renders immature GCs insensitive to inhibitory conductances, or there is a less interesting (and potentially misleading) possibility that the stimulus paradigm is insufficient to detect the functional consequence of the inhibitory conductance.
Because the SCN can communicate with target tissues through non-synaptic mechanisms (e.g., paracrine signaling, control of overt rhythms) [ 3], addressing the import of outputs from different SCN regions requires a functional assay that can detect the downstream consequences of cues transmitted by each SCN compartment.
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