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Here we found that, except for some pattern-based biclustering methods, most biclustering methods detected the type of modules, which they are designed to detect (Supplementary Fig. 24).
Furthermore, analysis of ultrathin sections of infected HFFF-2 cells by both immunofluorescence and immunogold revealed that EEA1-positive structures were very infrequent in the thickness of these sections, and thus by definition difficult to detect (Supplementary Figure S7).
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All possible SOxH oxidized forms were detected (Supplementary Fig. 8).
The peaks assigned to carbonates are hardly detected (Supplementary Fig. S5m).
However, in HBV-Tg mice, their expression could be detected (Supplementary Figure S6A D).
3,909 PREP1-enriched regions, or peaks, were detected (Supplementary Table S7).
Second, no significant correlations between expression strength and the firing rate or oscillatory power were detected (Supplementary Fig. 8).
From the 64 peptides of interest, 305 Rpom peptide transitions (peptide fragments) were detected (Supplementary Table S2).
Using the same cell clones, we further performed Southern blot analysis to investigate whether off-target integrants were detected (Supplementary Fig. 8a).
The reverse function of FoF1, ATP-dependent proton-pump activity, was also detected (Supplementary Fig. 8), suggesting the full functionality of the reconstituted FoF1-PLs.
Ramachandran statistics for the refined crystal structures showed 96 98% and 1 3% of residues in favored and allowed regions, respectively, with no outliers (0%) detected (Supplementary Table 7).
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