In line with what was observed upon glucose removal (Figure 1c), we did not detect significant changes in the abundance of the corresponding transcripts (Figure 4f).
DPBODPY consists of a terminal fluorophore and a selective ligand and was designed to detect significant changes in absorbance and/or fluorescence on metal ion binding.
While we did not detect significant changes in agrB transcription levels, atlE transcription was significantly upregulated in Brc.
The method was able to detect significant changes in tissue interstitial fluid under conditions of mild dehydration.
Although we detected Ca(2+) transient oscillations in the reprogrammed cells, we did not detect significant changes in resting membrane potential or spontaneously contracting cells.
We did not detect significant changes in hexokinase II activity during the treatment of HCT116 cells with 1.3 μM of RO5126766 for 24 hours (Figure 1f).
The small sample size was an addition limitation of this study, although it was sufficient to detect significant changes in GAG content.
We could not detect significant changes in candidate gene expression induced by EE in midbrain of Mecp2−/y mice.
In contrast, we did not detect significant changes in the minor axis of the varicosities (P>0.05, Student's t-test).
We did not detect significant changes in AGFP mRNA expression when comparing hemocytes with and without cactus mutations (Figure 6A).
Furthermore, under conditions of elevated transcription, and increased menin association with promoter regions, we were unable to detect significant changes in histone methylation.
