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On the other hand, the structured design for the whole equipment can realize the reciprocity fixing between the light module and the detect module.
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Finally, density-based methods detect modules by looking at contiguous regions of high density.
In this work, an existing tool maxClique was employed to detect modules from PPIN.
The simple comparison of modules detected by us and MCODE demonstrates that the integration of gene expression and protein interaction indeed helps to detect modules related to pathogenesis, where MCODE only exploits protein interaction information.
To see the significance of the identified modules, a popular tool, namely MCODE [46], that is developed to detect modules in a protein interaction network was utilized to identify modules in the pathogenic network.
Building on a theoretical foundation from Ling [9], the Miso methods accommodate the heterogeneity and noise that is inherent to genomic data and detect modules that vary widely in size, external isolation and internal cohesion.
We used simulated annealing (SA) algorithm [ 53] to detect modules in the HLMN.
Finally, these scores were used to detect modules using the exact Heinz method [ 56].
The 6000-gene teshowedowed that both metrics increase, allowing us to accurately detect modules even at lower recurrence rates.
In micro-organisms, computational methods have proven useful to detect modules of co-regulated genes [ 12, 13].
I used the Louvain method to detect modules, due to its rapidity and efficiency on large networks.
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