Sentence examples for detect linkages from inspiring English sources
Of the (48mbox750) families in the data, for (14mbox406) we could detect linkages to other families in the network.
We considered other possible explanations for the poor fit of the neutral model relative to the purifying selection model, including inability to detect linkages for some genes due to low expression, variation in the number of regulatory sites per gene, and microarray hybridization artifact, but these alternative models appear to be less plausible than the purifying selection model (see Text S1).
However, the number of transgressive genes for which we were able to identify genomic linkage was lower in aging worms, suggesting that a more complex polygenic regulation affected our ability to detect linkages at these ages.
When males and females were treated as one combined group (in order to increase the power to detect linkages with increased number of animals), the gender effect on expression was accounted for by subtracting the gender-specific mean from each expression value.
We examine the power to detect linkage disequilibrium for quantitative traits after phenotypic selection.
Consequently, the power to detect linkage through mod score will be highest when the space of models where the maximization is performed includes the true model.
Microsatellite genotyping is often used to detect linkage of known loci.
and that we did not detect linkage disequilibrium between these loci in either A. australis or A. rimitarae.
Cephalometric tracing and major measurements were followed as figure 3. The power to detect linkage was calculated using the program SLINK with 500 replicates.
For a set of 300 sibpairs the power to detect linkage is nearly 100% for an allele conferring a two-fold increased risk to siblings of affected individuals [47], [48].
This approach capitalizes on the fact that different family structures differ in their power to detect linkage [24] by successively considering the use of different splittings of the population pedigree.
