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It is therefore important to design and apply the tools to detect any safety lapses and to improve the quality of patient healthcare.
Survey results were reviewed by surveillance staff to detect any safety signals and compare adverse event frequencies among the different influenza vaccines administered.
Unlike prescription products, cosmetics do not benefit from a comprehensive pharmacovigilance program to detect any safety concerns that become evident with increased clinical use.
Our results are consistent with PsA-TT safety studies conducted in Burkina Faso and Niger using different surveillance strategies in which enhanced passive surveillance did not detect any safety concerns for the prespecified adverse events [ 21, 22].
While we recognize that this method of adverse event surveillance is biased to differently detect possible adverse events among patients that are randomized into the intervention group, we decided this protocol as a way to quickly detect any safety concerns regarding the intervention.
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A clinical event committee (CEC) has been formed to review and adjudicate reports prepared by the data coordinating group to detect any possible safety issue and/or related deficiencies in data collection if required.
Klein et al. studied a population-based cohort of 200,000 females, 44,000 of whom received all three doses of qHPVv; the findings from this large, comprehensive study did not detect any evidence of serious safety concerns secondary to qHPVv [61].
Neuropsychological parameters (test for attentional performance; TAP) will serve as a safety criterion to detect any deterioration in cognitive function and will be repeated at visit 11 (day 12) at the end of the treatment period.
Both pilots may detect a safety critical situation by their own observation.
They also produce better estimates in terms of statistical power to detect a safety signal when compared with cohort studies or case control studies, thus offering a possibility to overcome limited data resources such as in the present context [ 27].
A pooled approach combining the two studies and their respective extensions, with up to seven injections in total through 122 weeks, was planned to enhance the chances of detecting any signal on safety outcome measures.
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CEO of Professional Science Editing for Scientists @ prosciediting.com