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Case details were ascertained from hospital clinics and neuropathology departments across the region, and additional ascertainment checks undertaken for completeness were carried out with the National Registry of Childhood Tumours (www.ccrg.ox.ac.uk) and the Northern and Yorkshire Cancer Registry and Information Service (www.nycris.org.uk).uk
Treatment details were ascertained for 799 patients with heterozygous GCK mutations.
Demographic details were ascertained by questionnaire and included: age at presentation, symptom duration, level of education, gender, current, ex-smokers and non-smokers and mHAQ.
Demographic and pre-biopsy clinical data, including PSA history, digital rectal exam (DRE) results, smoking history, prostate volume and all biopsy procedure details were ascertained on case report forms.
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The data collection began in October 1974, and data such as maternal history, pregnancy complications, and delivery details are ascertained for each patient.
The details of the damage were ascertained at cellular level by electron microscopy.
Described in detail previously, incident diabetes cases were ascertained and verified by each participating EPIC center within the InterAct Project (10).
39 Our study has several strengths: the cohort was population based, the dietary questionnaire was validated, several potential confounding variables were ascertained in detail, and nationwide data linkage in Sweden allowed virtually complete follow-up and objective ascertainment of cardiovascular outcomes.
Details of the both forms of abuse were ascertained through the use of the Traumatic Antecedents Questionnaire [ 60].
Explanations of how these findings were ascertained will be discussed in further detail in this paper.
Baseline characteristics and detailed information of regimen modification until the end of 2010 were ascertained from cohort database and medical charts.
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