Details for the statistical analyses of other end points are listed in the Supplementary Data online.
For both frameshifts and premature stop codons, we find significant underrepresentation within protein domains (P in range <0.05 to <0.001; all of the P-values quoted for Tables 2, 3, 4, 5 are for χ2 tests; see Table 2 footnote for details of statistical tests).
Respondents reported their ethnic group in detail, but for statistical analysis ethnicity was categorized as 'white' or 'non-white' because of the small number of individuals in any ethnic minority sub-group.
All of the types of introns were carefully studied and compared (see Additional file 1: Table S6 for details of each type of intron; see Additional file 2: Figure S3 for the sequence logo for each type of intron; see Additional file 1: Table S7 for details of statistical analyses performed in this study).
Mutator populations also showed less between-population variability in cheat frequency than did the wild-type populations (reproduced with permission from [16], see this publication for details of statistical tests).
We refer to Extended Experimental Procedures for details of statistical analyses, fly stocks, diets, and more standard methods (immunohistochemistry, transmission electron microscopy, metabolic assays, survival assays, developmental rate and size quantifications, and in vivo recordings of neuronal activity).
Details of statistical analysis for each experiment were included in the figure legends.
Details of statistical analysis for all experiments are also provided in Supplementary Methods, available at Carcinogenesis Online.
Details of statistical weighting for the NSLAH can be found elsewhere (Vojta et al. 2002).
Details of statistical parameters used for the development of IC50 based QSAR models; Table S3.
