Detailed domain composition for each gene in each species is presented in the Additional file 3. Our data confirm the strong evolutionary conservation of the Notch pathway in bilaterians as all components are present in almost all the analysed bilaterian species.
Three aspects are discussed in detail: domain size distributions of the two adjacent monolayers within the film, optimal film thickness for a bilayer, and structural transition from a monolayer to a bilayer.
For each assay, PPDMs provides an overview of the assay details, domain architecture of the associated target and a form to submit a manual assignment.
Detailed time domain, Allan variance, and probability density function analysis revealed that both ARW and ARRW are of Gaussian type and Coriolis-uncorrelated, showing stable in-operational noise performance of the reported gyroscope.
For example, May's [ 49] framework described only two domains (agency and context), and Aaron et al.'s [ 33] framework detailed three domains (outer context, inner context, and innovation); however, the components within the framework fitted four domains as per the definitions of analysis provided in Additional file 1.
Besides, this is not a "black box" approach, as the methodology is open to embed information coming from other UML diagrams (possibly in late lifecycle phases) for detailing, refining or domain tailoring the performance model.
We show that our FMC is capable of performing detailed multi-domain design space exploration of realistic automotive architectures.
Detailed time-domain dynamic finite-element method (FEM) analysis showed that the pipe wall experienced denting, but this was within the allowable limits.
A useful summary of the structure and active sites of caspases is provided, detailing how these domains interact with each other or with their adaptors and more than 1000 substrates.
Detailed functional protein domain analyses have previously been conducted for both SNX9 [41] and SNX33 [54], so we decided to focus on SNX18.
