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To the best of our knowledge, this is the first demonstration of using OCT to visualize the detailed capillary network within renal cortex in vivo.
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These villi are subsequently vascularized with an elaborate capillary network.
The recent development of the OMAG modality was reported in [ 31, 38] to have an ultrahigh system sensitivity to the slow blood flows, down to 4 μm/s, which has been successfully employed to obtain detailed micro-capillary networks of different biological tissues in vivo, e.g., retina, skin, brain and cochlea [ 31, 39– 42].
Adenoviral delivery of a chimeric protein, in which the N- and C-terminal propeptides of VEGF-C flanked the VHD of VEGF-A, resulted in a denser and more fine-meshed lymphatic capillary network than VEGF-A165, although the detailed mechanism has not been reported7.
By far the greater part emerges from the liver's capillary network in its pure and pristine state.
These lie between loops of the glomerular capillaries and form a stalk or scaffolding for the capillary network.
To further determine the effect of FG-4592 on capillary network formation in vitro, HUVECs tube formation assay was performed.
The paracortex and medulla showed a dense capillary network with areas of tortuous capillaries, sometimes forming glomerular arrays suggesting nonsprouting angiogenesis by capillary elongation.
The filtration unit of the kidney is the glomerulus, a capillary network supported by mesangial cells and extracellular matrix (ECM).
Lower vertebrates have two so-called portal systems, areas of the venous system that begin in capillaries in tissues and join to form veins, which divide to produce another capillary network en route to the heart.
Understanding the formation and structure of a capillary network is critical for any reparative strategy since the capillary network dictates tissue survival, hemodynamics, and mass transport.
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