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This ensures that the decrease in the cell adhesion is optimal for cell rearrangements without being destructive to tissue integrity.
While a useful and rapid hemostat, heat-based hemostasis is destructive to tissue architecture, leaves cytotoxic tissue debris, and creates a pro-inflammatory environment.
This paper describes a simple method, mPREF, for the extraction and analysis of small molecular weight biomarkers from tissue specimens that is non-destructive to tissue and is compatible with downstream histology analysis, such that histopathology and biomarker analysis can be performed on the same exact tissue.
Molecular biomarkers have also been described that are associated with cancer aggressiveness, however, the portion of tissue analyzed is often processed in a manner that is destructive to the tissue.
Most inflammatory muscle diseases are destructive to the tissue involved and to the surrounding areas.
High-energy neutrons, though short-lived, could penetrate armour or several metres of earth and would be extremely destructive to living tissue.
The biopsy process itself is inherently destructive to the tissue, and subsequent cartilage pathology may be induced as the self-repair ability of articular cartilage is highly limited.
The fundamental biological properties of neutrophils as short-lived, innate immune cells that secrete proteases, oxidants, and inflammatory cytokines and chemokines (Elkington et al., 2011; Palanisamy et al., 2011; Amulic et al., 2012; Wilkinson et al., 2012; Gopal et al., 2013; Dorhoi et al., 2014; Nouailles et al., 2014) support this concept that neutrophils are destructive to lung tissue.
We report here a new method for the extraction of molecular biomarkers from human tissue that is non-destructive to the tissue and is compatible with downstream workflow including histopathology and immunohistochemical analysis.
However, by the same process, they are also destructive to healthy host tissue.
Xanthogranulomatous inflammation is an uncommon form of chronic inflammation that is destructive to the normal tissue of affected organs.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com