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The destructive stimulus may impair the ER function and leads to the activation of unfolded-protein-response-ER stress [ 18, 19].
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The molecular and cellular machinery, which is switched on in response to destructive stimuli, is very similar in case of burn, cutaneous wounds, myocardial infarction, spinal-cord damage, and visceral injuries [1].
"No more stimulus" has become the destructive mantra of conservative politicians here and across Europe.
An underlying defect in the activity of the cholinergic anti-inflammatory pathway may trigger an overwhelming and self-destructive immune response to an otherwise innocuous immunological stimulus and thus contribute to disease pathogenesis [3], [33].
While Black Friday can be an amazing stimulus for one day, it can be destructive if it goes on too long.
The Liberal Democrats have promised greater economic stimulus spending and more action to end a destructive cycle of declining prices.
One of the things you always heard, back when we were actually talking about stimulus rather than fighting a rearguard action against destructive austerity, was the claim that stimulus spending would inevitably end up becoming a permanent fixture of the economy.
Unfortunately, Arne Duncan, head of the US Department of Education, is forcing more districts to adopt these destructive policies, by making this a condition of their eligibility for federal stimulus funds.
The concept that has emerged from these observations is that ANCAs and proinflammatory stimuli (most likely of infectious origin) synergize to cause a destructive inflammatory process.
Despite their destructive activity they are also signalling molecules, priming the acclimatory response to stress stimuli.
But the I.M.F. is well respected, and its warning of deflation, a destructive plunge in prices, could help give the central bank the economic rationale to use the stimulus of buying billions of euros in government bonds.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com