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No difference in cartilage destruction was detected in Wt and Bid-/ mice (data not shown).
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Evidence of extra-sinus tissue involvement and/or bony destruction were detected in 15 (33%) of patients with IFS.
Unfortunately, the use of radiological-methods is not without limitations, as significant joint-damage has taken place, by the time, signs of joint-destruction are detected by X-ray [ 13, 14].
At E14.5, lung tissue destruction with massive hemorrhage was detected in Apc CKO mice, explaining the lung contusion observed within the whole body view (Fig. 2a).
Of relevance for joint diseases, Gal-3 was shown to localize in the synovium obtained from rheumatoid arthritis patients at the sites of cartilage and bone destruction, whereas Gal-1 was detected mostly in the sublining layer [ 52].
Using light microscopy, an infiltration of neoplastic cells in the capsule and parenchyma, with destruction of the kidney architecture was detected.
In mice, only at 8 months after infection, infiltration and destruction of the lamina muscularis mucosae was detected in 1/3 of the animals.
administration of plasmid DNA in mice, an adaptive immune response that mediates the apoptotic destruction of vaccine antigen-expressing myocytes was detected [ 161].
In GUS and GMUS, partial destruction or disintegration of the cell membrane was detected.
After calcination, the formation of zincite was detected in the LDH, indicating the destruction of the lamellar structure.
Isopropylmethylphosphonate was detected as a main primary phosphorus-containing product of the destruction of DIMP.
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