Exact(1)
Considering that Tregs are selective targets for destruction, expression profiling within Tregs provided us with a model for understanding the cause (Treg environment) by studying the effect (Treg expression changes).
Similar(59)
That it should be a Henry vacuum, the shamelessly anthropomorphised device, makes it even better: as he approaches Saville's giant works, ready to wreak destruction, his expression will be one of eternal cheerfulness.
Besides coding regions and introns, Muller's ratchet should also lead to the weakening or even destruction of expression signals in the 5' and 3' UTR of mRNAs.
Finally, injection of FK866 (intraperitoneally or intra-articularly) blocked Ad- Epas1-induced cartilage destruction and expression of NAMPT target MMPs (figure 6C and online supplementary figure S7C).
To investigate the effect of oral administration of THR0921 at the site of joint destruction, the expression levels of TNF-α, IL-1β, MCP-1 and RANKL mRNA were examined by real-time RT-PCR analysis.
This is the American mode of denial: we frame acts of destruction as expressions of democracy.
Using the Connectivity Map, we identified GHK as a compound that can reverse the gene-expression signature associated with emphysematous destruction and induce expression patterns consistent with TGFβ pathway activation.
UNESCO Director Irina Bokova condemned the latest attack in Palmyra on Monday, saying that the destruction "embodies an expression of pure hatred and ignorance".
In contrast, upregulation of HMGB1 mRNA was restricted mainly to synovial tissue adjacent to areas with cartilage and bone destruction, where the expression was pronounced with cells expressing numerous grains.
In pathogenic primary culture chondrocytes treated with IL-1β (the primary inflammatory cytokine involved in cartilage destruction), however, Lrp5 expression was dramatically increased in a dose-dependent manner and a time-dependent manner, whereas Lrp6 expression was constant.
HIV-1 Tat protein induced barrier destruction, changes in expression of TJs, and activation of ERK1/2 and NF-κB were abrogated by inhibitor of ERK1/2 and NF-κB.
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