Sentence examples for destroys cohesion from inspiring English sources

In other words, it is cohesin's "releasing activity" that destroys cohesion built in the absence of Smc3 acetylation.

To understand better how Wapl destroys cohesion, we addressed the nature of its association with chromosomal cohesin.

Our experiments imply that cohesin's releasing activity not only promotes cohesin's turnover on chromosomes but also destroys cohesion once it has been established.

This result demonstrates that an activity dependent on Wapl does not merely (if at all) prevent creation of cohesion; it actually destroys cohesion that has already been established.

The simplest explanation for this result is that, in the absence of Eco1, cohesin's releasing activity destroys cohesion by disconnecting the Smc3/α-kleisin interface, permitting DNAs to escape from cohesin's embrace.

How then does antiestablishment destroy cohesion?

First, Wapl should be capable of destroying cohesion long after its establishment.

Our finding that Wapl is able to destroy cohesion long after replication is complete in cells lacking Eco1 is consistent with the latter hypothesis.

This model proposes that cohesion is the result of topologically embracing the two sister DNA molecules within a cohesin ring and that opening of the ring, due to cleavage of its Scc1 subunit by separase, liberates the sister chromatids, thereby destroying cohesion.

Losing ground in this area has long-term consequences and destroys social cohesion.

These proteins may be major components of the extracrystalline matrix (discussed below), in agreement with previous reports indicating that prolonged treatment of brachiopod shells with hypochlorite removes the electron microscopically visible extracrystalline matrix and destroys the cohesion between calcified elements of the shell (Collins et al. 1988).