Sentence examples for destroy the functionality of from inspiring English sources
In this work, the influence of GU base pairs on the effectivity of translation attenuation by miRNAs is assayed by mutating binding sites and comparing attenuation effectivity to wild type binding sites Introducing three GU base pairs into the mRNA/miRNA duplex did, with only minor changes to the binding energy, almost completely destroy the functionality of the binding site.
Joining of nanostructured metals by conventional processes, such as welding, often destroys the functionality of the material by disrupting its microstructure within the heat-affected zone.
Vincristine's antineoplastic effect is basically attributed to its ability to bind to the protein tubulin, thereby destroying the functionality of the cell's microtubules, which form the mitotic spindle, and ultimately resulting in apoptotic cell death at mitosis (an M-phase specific drug) [30] [32].
Nevertheless we investigated the NLS in more detail and showed that mutations destroying the functionality of the NLS did not completely abolish the nuclear translocation of either the N-terminal or the full length GFP fusion proteins in either aPKC.
The fact the residue is not absolutely conserved, however, means that the site can tolerate some degree of variations without destroying the core functionality of the protein, such as folding or catalytic activity.
The GO nanosheets did not destroy the alignment of nanofibers.
They significantly destroy the philosophy of P2P file-sharing networks.
