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Other vectors were destined for expression of active CK-B or CK-BC283S, a catalytic-dead protein, both with N-terminal extensions consisting of the FK506-Rapamycin Binding (FRB) domain.
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It also means that SYT-SSX2 binding to enhancer elements may be a specific feature for genes destined for altered expression.
Although reaper and grim are only expressed in cells that are destined for death, hid expression is controlled at both the transcriptional and post-transcriptional levels (reviewed in Bilak and Su).
In method 2, cDNA synthesis (S2 - S6; destined for the differential gene expression analysis) was performed following a previously described RNA amplification protocol [ 52].
The endoplasmic reticulum (ER) has two vital roles in the cell – it is a major intracellular calcium store and it enhances post-translational modifications of newly synthesized proteins destined for secretion, cell surface expression or organelle biogenesis.
Alternatively, down-regulation of endogenous proteinase activities by means of RNA interference has been attempted for improvement of the performance of plant-based expression platforms destined for the production of protein therapeutics [ 9].
Collectively, these results indicate that down-regulation of endogenous serine and cysteine proteinase activities could be used to improve the performance of plant-based expression platforms destined for the production of biopharmaceuticals.
The increased expression of proteins destined for secretion during the immune response triggers the unfolded protein response in the ER.
Evidence also showed that Treg-associated gene expressions in recipients destined for graft tolerance and rejection primarily differed within the transplanted grafts themselves rather than systemically or in spleens and draining lymph nodes of recipients [ 18].
Such mechanisms should be reflected in differences in gene expression between developing larvae destined for different castes.
Molecular strategies for monitoring the gene expression patterns of chondrocytes destined for ACT were developed recently for the quality management of therapeutic cell culture and the safety of ACT patients [ 8, 9].
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