Sentence examples for destabilizing the structure and from inspiring English sources
Low levels of proBias enabled fissures to reach toward the SMS center, destabilizing the structure and causing chaotic, uncontrolled growth.
Although this insertion could originate from a random mistake in the splicing process, the absence of stop codons or cysteine residues (which would destabilize the structure) and the fact that it keeps the translational phase are indicative that it could result in a new protein product.
Contacts involving many beta-branched hydrophobic residues in the crowded protein core may generate strain in helices, destabilizing the structure.
Furthermore, all nonsense or mutations of deletion in Gigaxonin are likely severely destabilizing the structure, by improper folding of the β-propeller that constitutes the KELCH domain.
Indeed, the major dense line is exceptionally stable, even when deliberate attempts are made to destabilize the structure (Sedzik and Blaurock, 1995).
We observed that longer fatty acids progressively destabilize the structure of ACP and increase micro- and millisecond motions in residues surrounding the fatty acid binding cavity.
Our in silico modeling of the effects of these three missense mutations of the wt properties of ZC4H2 protein predicted that the mutations would destabilize the structure of ZC4H2 and thus would indirectly affect its function.
Although this residue (Cys284) is not at the active site for hydrolytic activity of PON1, its mutation or blockage is likely to destabilize the structure of PON1 and affect its function (Harel et al. 2004).
This additional repulsive energy would decrease the stability of bonds between layers and destabilize the structure of myelin.
A subset S of features that act as penalties are constrained to positive values, x j >0 for j∈ S. The set S is defined along the following principles: unpaired loop regions destabilize the structure relative to a random coil and hence should be penalized.
