Sentence examples for destabilizing the interactions between from inspiring English sources

Specifically, the proton is transferred from C136 to C558′ (through WAT) and then from C558′ to C559′, each proton transfer being used to drive the transfer of Hg2+ toward the active site by destabilizing the interactions between the targeted thiolate and Hg2+.

Changing the position of the macrocycle in a well-determined way is possible, by making the binding affinity of the less occupied station more favorable, or by destabilizing the interaction between the most occupied station and the macrocycle.

ATP counters the AMP effect not only by competitively binding to the γ-subunit, but also by destabilizing the interaction between the AID-αRIM and the γ-subunit independently of adenine nucleotide binding to CBS-3.

If these SNPs will be experimentally confirmed, they could have the effect of destabilizing the interaction between the miRNA and the mRNA, which could consequently avoids cleavage and lead to phenotypical variations in developmental features or in the resistance to viral infection.

We show that binding of ibuprofen to Aβ destabilizes the interactions between incoming peptides and the fibril.

The chosen mutations destabilize the interaction between the fusion peptide and the rest of HA in the pre-fusion state (the structure of which has been determined by X-ray crystallography).

The N329S mutation will not allow the latter H bond interactions and therefore is likely to destabilize the interaction between α- and β-tubulin monomers around H6 and the B5 H5 loop, possibly affecting the conformation necessary for GTP binding.

Importantly phosphorylation of H3T3 destabilizes the interaction between the N-terminal tail of H3 with UHRF1, while H3S10 phosphorylation strongly reduces the affinity of TTD-PHD for the H3K9me3 tail.

Thus, phosphorylation at this residue would cause electrostatic repulsion, destabilizing the modulatory interactions between the CTN helix and AIE region, resulting in enzyme activation.

Since ATP destabilizes the AID-αRIM1/2 interaction with core AMPK, binding of the larger ATP likely indirectly destabilizes the interaction of αRIM-1 with the nucleotide-free CBS-2.

The analogous mutations in human PDCD4 destabilize the interaction with eIF4A (Chang et al., 2009; Waters et al., 2011).