But rather than treating this destabilized state as a state of risk, to be analyzed and resolved as appropriate – controlled through mechanisms appropriate to a problem, dilemma, or paradox – one responds to the state of affairs as one might to an uncaused effect – puzzled, entangled, attentive.
A bold approach is needed to reform the DRC's governmental apparatus, the collapse of which not only affects its citizens, but also destabilizes states throughout the continent and provides a haven for terrorists, arms traffickers, and criminal networks.
One aim is to understand the molecular interactions that maintain cells in a pluripotent state, destabilize this state leading to commitment, as well as allow a return to the pluripotent state from a committed state.
Refugees pour out of the country, destabilizing neighboring states.
This is not to say the actions of the Egyptian government are meritless, as they have repeatedly stated that they were attempting to combat domestic terrorism aimed at destabilizing the state.
"The Taliban and the jihadi elements are very much opposed to Shiites, and this suits their double purpose of destabilizing the state while creating despondency amongst the people, and especially the Shiite," said Talat Masood, a retired Pakistani general and military analyst.
That the C-terminal mutants shifted the VDA suggests that the C-terminus contributes to activation gating mechanism by stabilizing the closed state or destabilizing the open state without affecting the kinetics of activation.
While the administration is trying to stop Mr. bin Laden from planning and financing terror aimed at Americans, both in the United States and abroad, Russia wants to stop the Taliban from supporting Muslim militants fighting Russian forces in Chechnya and from destabilizing neighboring states in Central Asia.
These findings identify a cell-intrinsic rheostat for destabilizing ground-state pluripotency to allow lineage commitment.
No significant change was observed in τ closed, suggesting that Yoda1 mainly stabilizes the open state rather than destabilizing the closed state.
We further show that the transitions between behavioral states were regulated by the GSA-1(Gαs) pathway: increased Gαs signaling stabilized the active wakefulness state both within and outside of lethargus, while decreased Gαs signaling destabilized this state, but only outside of lethargus.
