This support the notion that increased production of MMP-1 may destabilize the organization of new granulomas, thus contributing to the dissemination of infected cells and disease progression.
Many angiogenic molecules can destabilize the organization of intercellular junctions, causing endothelial barrier opening [ 8- 13].
A bunch of sudden and abrupt changes will leave everyone lurching, and threatens to destabilize your organization.
"The results indicate that the illegal killing of elephants can erode the genetic basis for their social structure but does not necessarily destabilize their social organization".
Increased MMP-1 availability and activity early in M. tuberculosis infection may destabilize granuloma formation, in particular the correct organization of new granulomas, promoting spread of the infection and progression to active TB.
Parallel β-sheet organization will create electrostatic repulsion destabilizing the fibril, whereas an antiparallel β-sheet organization simultaneously juxtaposes the central hydrophobic segment and minimizes the electrostatic energy.
But she acknowledged the destabilizing fault lines in the organization, saying: "Conservation countries will never agree to permit commercial and lethal scientific whaling, in my view".
Generally, applying power assist destabilizes the system.
"It was very important for the Qataris to understand that Nusra is not only an organization that destabilizes the situation in Syria," said one senior Obama administration official.
Bush administration officials say that Jemaah Islamiyah fits all the criteria to be listed as a terrorist organization, but the United States has refrained from doing so for fear of destabilizing Indonesia politically and making life more difficult for President Megawati.
