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There's no more damaging and destabilizing message the government can send than this idea that if you're big, the government will get you out of trouble".
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Although miRNA are thought to down-regulate expression of genes by binding to the 3′ UTRs of target transcripts and destabilizing the message, cancer studies have demonstrated that the relationship between miRNA and mRNA abundance is complex and that there are as many positive as negative correlations [ 37– 40].
However, additional genotyping [ 15] and, independently, complete resequencing of the risk haplotype, pointed to a deletion in the 3' untranslated region (UTR) of predicted transcript LOC387715 that destabilizes its message, suggesting that loss of that transcript, and not HTRA1, drives the susceptibility to AMD [ 16].
Surprisingly, we found that HuR does not act as a stabilizing factor upon expression of these Eph/ephrins, but that it destabilizes the respective messages.
Schapiro told Czech journalists that he recognized Russia's contribution to quashing Nazi forces, but insisted that the act of Zeman "standing on a platform reviewing a [Russian] military parade at a time when that military is destabilizing a European nation is not really a good message to send".
"We have an interest in sending a message to Iran and the world for that matter about just how destabilizing a nuclear proliferation would be in the Middle East," he said.
Napster was enormously destabilizing.
"This was very destabilizing.
It's very destabilizing.
"It is upsetting and destabilizing.
The disease was very destabilizing.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com