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And thanks to the Internet, I can now seek out mentally destabilizing facts to confirm theories I'd rather not believe because he is frozen in time in my brain.
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If most of such functional mutations are destabilizing, owing to the fact they compromise ancestral functions, robustness to these mutations may fuel biological evolvability [ 19].
This suggests that apo-BtGH84 is in fact destabilized by activator binding in the absence of any ligand in the active site.
Only live imaging of the dynamics could reveal that the mutant termini did not have a primary targeting defect, but are in fact destabilized after reaching to the correct target.
This is most likely explained by the fact that the nonunions have not been assessed to represent a destabilizing ligament injury but only a bony nonunion.
The generality of this stability-function tradeoff must be viewed within the context of the fact that regardless of their effect on functions most mutations are destabilizing [21], [22], [23], [24].
The fact that our allies even have to consider such a possibility is destabilizing.
In fact, reduced oil dependence, by putting downward pressure on oil prices, could actually be destabilizing.
President Obama has yet to fully implement this law in spite of the fact that his own government has said that "credible evidence" exists that Rwanda is destabilizing the Congo.
In fact the entire cell, its membranes, organelles, and transport systems are subject to stabilizing and destabilizing forces that couple to curvature.
In fact, because it costs more, Social Impact investing raises this debt burden while delaying it, thereby destabilizing the public system further.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com