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Both encapsulated compounds behaved differently in the in vitro cell uptake, which was also influenced by serum concentration, where serum albumin was found to be the primary destabilizing component.
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The regulation of synthesis often depends on the presence of small regulators, such as ppGpp or on mRNA stabilizing or destabilizing components.
It is demonstrated that each component of the composite destabilizes the other component in a specific composition range by the formation of NaMgH3.
Moreover, the drug molecules added into SM/Chol film treated as model raft system drastically decrease molecular packing, weaken the interactions between raft components, destabilize the system and alter its morphology.
In Saccharomyces cerevisiae, alteration of these components destabilizes the oligomeric structures, leading concomitantly to the appearance of monomeric species of ATP synthase and anomalous mitochondrial morphologies in the form of onion-like structures.
It is therefore conceivable that repressing LUBAC components destabilizes TNFR1-CI and facilitates necrosome formation.
We argue that the main role of the newly recruited (nuclear encoded) ribosomal- and OXPHOS proteins is to provide structural compensation to the mutationally destabilized mitochondrially encoded components.
The effect of higher frequency components is insignificant when their amplitude is small as compared to the amplitude of fundamental component; however, non-small high frequency components may have stabilizing or destabilizing effects.
This is solved by numerical methods demonstrating that the ky component is coupled to only stabilizing quantities while the kx component couples to the competing stabilizing and destabilizing parameters.
The presence of these rare codons may cause stalling during translation, thereby destabilizing the transcripts by leaving the mRNA exposed to components of the RNA degradation machinery.
The uncertainty-based design concerns the noise estimator, so as to prevent the model error from conveying uncertainty components which are command-dependent and thus prone to destabilizing the controlled plant.
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