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Such destabilized cells adapt to their environment by traveling towards low-fluctuation states.
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This action appears to destabilize cell adhesion for subsequent shrinking, membrane blebbing and eventual death.
Saponins are known to destabilize cell membranes hence increase cell permeability by combining with membranes associated sterols [ 44].
SRC phosphorylation of E-cadherin is known to increase its internalization, subsequently destabilizing cell-cell junctions [ 19].
In still another, electric shocks are used to destabilize cell membranes, making them permeable to delivered genes.
Taken together, the results indicate that expression of RASSF1C destabilizes cell-cell junctions and disrupts further recycling of E-cadherin via SRC.
In this species, β-Glc Y binds to AGPs and destabilizes cell wall assembly by blocking the deposition of pectin material in the cell wall.
These findings raise a number of questions: are there other small proteins that can destabilize cell membranes in a similar manner to defensins?
These results are reminiscent of published studies in cancer biology that show that activation of EGFR destabilizes cell-cycle inhibitor proteins to enable quiescent cells to enter the cell cycle (Lenferink et al., 2000; Boerner et al., 2005).
Molecular simulations of lipid bilayers have shown that both incremental shear and tension can destabilize cell membranes, and that the energy that is required to cause such membrane damage can be achieved with rotating magnetic nanoparticles.
During fermentation, the ethanol concentration increases and can destabilize cell membranes in a manner that may result in an inability to take-up nitrogenous compounds from the must [ 2].
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