Sentence examples for destabilization of both from inspiring English sources

In the case of A1273V, we show destabilization of both channel activation and fast inactivation at elevated temperatures.

Moreover, the gravity expedites the destabilization of both the modes in the inclined channels as compared to the similar non-inclined channels.

Then the oxidation-induced destabilization of both the loop connecting Strand-2 and Helix-2 and the C-terminal region of Helix-2 and part of the loop connecting Helix-2 and Helix-3 looks likely to be an essential step on the productive route of conversion.

It has been demonstrated that the absence of Dpy19l2 leads to the destabilization of both the nuclear dense lamina and the junction between the acroplaxome and the nuclear envelope, preventing the anchoring of the acrosome to the nucleus [ 19].

Consistent with this observation, the srb4-138 mutant, with an apparent destabilization of both regions, exhibits a Mediator complex that consistently breaks apart at the Head/Middle inter-module boundary.

These results can be explained if the 18-fold lower binding affinity of MutS for CC relative to that for GT (Kd values of 40 nM for GT and 720 nM for CC) results from destabilization of both B and U but not I.

Trans-alkylation induces inactivation and destabilization of the protein, both in vitro and in vivo, likely triggering conformational changes.

In the AR WT antiandrogen R-bicalutamide complex, destabilization of M895 by both W741 and the sulfonyl linkage of the ligand may be responsible for reported antagonism.

Yi and Richards reported destabilization of phenotypes in both the bal and cpr1 mutants in more than 10% of EMS-treated plants in the M 1 generation.

Hence a sudden rise of pressure could be at the origin of both the muffled noise and destabilization of the dump mass.

OA was induced via surgical destabilization of the medial meniscus in both genotypes, and disease progression was monitored on histological and molecular levels.