Sentence examples for destabilization elements from inspiring English sources
Novel 3' variants can be non-neutral for instance when containing regulatory motifs such as miRNA targets or destabilization elements, or when affecting translation efficiency through the sheer effect of 3' UTR size [ 17].
Meanwhile, mA-IP-seq analysis reveals that the localization of destabilization element of c-myc also overlaps with mA peaks [24].
Moreover, even if the ADH1t is not acting as terminator of the AS, it can introduce a destabilization element that leads to its rapid degradation.
"They're playing this very dangerous game of destabilization by having elements of the ISI and the army sympathetic to the Taliban and Al Qaeda elements".
The design of insulin analogues has emphasized stabilization or destabilization of structural elements according to established principles of protein folding.
In contrast to the weak light-induced changes observed for PtAu1aLOV, measurements on PtAu1afull revealed pronounced destabilization of several elements of the LOV domain upon illumination including Jα and A´α.
Its multidisciplinary base creates several difficulties: It may produce management barriers with a risk of destabilization if an element of service is withdrawn; financially, it is a challenging resource; and data capture and analysis are important if its cost-effectiveness is to be evidenced adequately.
Since slowly exchanging amides are involved in the exchange of the aforementioned elements, the observed destabilization can be interpreted as an increase in structural dynamics.
This sequence element promotes mRNA destabilization in the non-flagellated mammalian (amastigote) stage.
Such anomalous destabilization of genomic structures by Alu elements, especially those of the youngest Alu-Y family, is known to cause enrichment of SNPs in their vicinities [13], [14], and may contribute in the present instance to the high sequence diversity of the S1 S29 segment.
Linear elements are removed for destabilization more frequently than circular ones in construct I frames because they stabilize the short fragment as the only holding element, while linear elements can be more than one, and they can be progressively removed.
