The unexpected incorporation of potentially charged histidine side chains within the hydrophobic core of the trimeric assembly led us to speculate that protonation of these groups might provide a mechanism for destabilisation of the assembly, hence potentially initiating or assisting flexibility within the rod-like structure.
Other processes, often involving causal interactions between entities from distinct levels of biological organisation, or operating at different time scales, are responsible not only for the destabilisation of pre-existing entities, but also for the emergence and stabilisation of novel entities in the microbial world.
This is even more important when "we" arguably have a moral responsibility – through our foreign policies – for the destabilisation of countries such as Syria and Libya.
But the deployment of large numbers of well-equipped, combat-ready troops has proved useful, to intimidate and provide psychological support for the destabilisation of eastern Ukraine by pro-Russian separatists.
In this study however, we, have expressed PLN RΔ14 in the complete absence of any WT PLN, and the finding in this study that PLN RΔ14 is not recovered by COP I mediated retrograde transport and has becomes localized at the plasma membrane offers a mechanism by which the concentration of PLN is reduced in the ER and a possible explanation for the destabilisation of the pentameric form of PLN.
(28-year old married father of two; chronic cougher) Frequently mentioned as a reason why women have extramarital sexual relationships, adequate provision was thus seen by men as essential for avoiding destabilisation of their family by unscrupulous members of the community.
Russia is heading for recession next year, partly because of the sanctions imposed by the EU and US as punishment for Putin's destabilisation of Ukraine.
"If these two regions were given a special status within Ukraine, they would become Putin's instrument of destabilisation of Ukraine, his instrument for shackling Ukraine in certain geopolitical limits, like Trans-Dniester in Moldova or South Ossetia and Abkhazia in Georgia".
Applications of atomic force microscopy (AFM) and scanning near-field optical microscopy (SNOM) to study protein-surfactant interactions at air water and oil water interfaces has revealed new and unexpected generic models for the surfactant-induced destabilisation of protein-stabilised foams and emulsions.
