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Dear Editor, Despite tremendous effort devoted to the development of antiretroviral therapies to combat HIV over the past decades, AIDS remains one of the most important global infectious diseases.
Despite tremendous effort, a large number of clinical trials failed to demonstrate additional survival benefit in using systemic therapy compared with gemcitabine alone.
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Despite tremendous efforts on both sides, vicious insurgent wars in Central America failed to overthrow a leftist regime in Nicaragua or rightist regimes in El Salvador and Guatemala.
Despite tremendous efforts, developing ORR catalysts with high activity at low cost remains a great challenge.
However, despite tremendous efforts, no unequivocal proof of therapeutic efficacy could be shown in AD patients.
Despite tremendous efforts, developing ciprofloxacin detection method with accuracy and sensitivity at low-cost remains a great challenge.
Despite tremendous efforts to develop stem cell-based tooth regenerative strategies, the identification of intrinsic properties of pulpal stem cells is an unresolved question.
Despite tremendous efforts in developing osteochondral plugs, formation of the osteochondral interface with proper zonal organization has not yet been reported.
Despite tremendous efforts, designing and preparing water, chemical, and moisture stable porous coordination polymers (PCPs) with carboxylate ligands remain a challenge.
Despite tremendous efforts, it is still a great challenge to design efficient visible-light-responsive ZnO-based photocatalysts for hydrogen production.
What's more, the specific ethanol productivity from xylose was an order of magnitude lower than that from glucose, despite tremendous efforts, and the ethanol yield from xylose was lower than that from glucose as well (Matsushika et al. 2009b).
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CEO of Professional Science Editing for Scientists @ prosciediting.com