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Despite this staging system, the clinical behaviour of melanoma is often unpredictable (Nagore et al, 2005), because melanoma is a group of diseases with various biological subtypes (Lomas et al, 2008).
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Despite this advanced stage of clinical testing many fundamental questions regarding the tentative IL-24-mediated selective killing of cancer cells remain to be answered.
Treatment with PEDF was delayed until orthotopic osteosarcoma was macroscopically evident, and despite this late stage of intervention, we observed 47.4% and 53.0% reductions in tumour volume by the study end point for 50 and 500 μg kg−1 PEDF, respectively.
Tasting is vital at every step of cake making, and I love tasting this stage, despite the raw eggs.
At this stage, despite Clinton's troubles, the likelihood remains that they will make it six out of seven.
Mr. Faizi said Mr. Karzai had decided against including Kandahar at this stage, despite requests from community leaders to do so.
Mr. Bronner said he had no regrets about investing in the airline, despite the difficulties in this stage of the reorganization plan.
He would not confirm if the company was already in talks with supermarkets about price rises, although he did say ABF had not increased the price of Twinings tea at this stage, despite talk of price rises by rival Typhoo.
News of the arrest caused surprise in Northern Ireland, since most people had assumed the incident was unlikely to generate new developments at this stage, despite a lengthy police investigation.
I would like to add that, despite my reservations at this stage, I am very grateful for what Johann Malawanna, the chair of the junior doctors committee of the BMA, has done.
However, the initial growth stage (when catalysts droplets form small NWs) was overlooked, despite the fact that this stage is the most important one for understanding the growth process.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com