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Despite this depletion there was no observable relationship with the tumour response.
Despite this depletion, however, the inactive allele of the two genes was still methylated at similar levels between the control and knockdown cells (Fig 3).
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In conclusion, cisplatin treatment caused significant Mg and K depletion in the majority of patients and, in most patients, this depletion was observed despite normal corresponding P values.
The retention of Oct4 and Nanog expression, despite the depletion of Sox2 in this study, should be viewed in the light of their own auto-regulation which is likely to allow their transcription and translation even in the absence of Sox2.
In October Haig, determined to carry on despite the depletion of his armies, now turned to the Canadians.
The iron industry continued to expand in the 1890s, despite the depletion of local natural resources.
Despite the depletion of CD8+ cells, there was no increase in HSV-2 shedding in the vaginal swabs.
Despite the depletion of protein reserves the starved fish were still able to mount an APR, or at least induce expression of the genes.
Despite the depletion of MyoA and MTIP protein from the P clag - cdpk1-gfp ookinetes, their mRNA levels were unchanged, an observation we confirmed for mtip mRNA by northern blot analysis.
Interestingly, translocation of STIM1 EYFP now occurred despite the depletion of phosphoinositides in cells where Cerulean Orai1 was also overexpressed with the mean number of puncta per cell not significantly different from control untransfected cells treated with thapsigargin.
The high plasma levels of immunoglobulins despite the depletion of peripheral B-cells in old Plg −/− and MMP9 −/−:Plg −/− mice might be due to long-lived plasma cells situated in the bone marrow, which are independent of repopulation by the memory B-cell compartment and can thus maintain antibody production regardless of the peripheral B-cell depletion (DiLillo et al., 2008).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com