When depositing on Si, doping nitrogen into carbon improved the electrochemical properties despite weak adhesion to the substrate.
After deformation, these brittle islands can remain crack-free, and the TFTs achieve comparable device behavior despite average strain in the substrate in excess of 5%.
On the other hand, wetland plants increased the pH, decreased the redox potential, and increased the metal concentrations in the substrate, despite the fact that metal uptake in the studied wetland plants accounted for only 0.002 2.9% of the annual metal loading into the wetlands, suggesting that plants promote metal sedimentation and adsorption.
Unexpectedly, despite the absence of the substrate or products in the active site, the two domains of SA PpaC form a closed active site, a conformation observed in structures of other family II PPiases only in complex with substrate or product mimics.
One explanation for the reduced APP cleavage in adult brain despite the presence of the substrate could be that γ-secretase and APP are spatially separated in the membranes.
Despite the differences in the substrate specificity, the cohort of domain hits i.e., MIP, Voltage_CLC, Form_Nir_tranp and ECF-ribofla_trS generally describes a channel protein that transports its solute across the lipid membrane.
Despite the similar substrate preference of GLuc and NLuc, dihydropyridines are selective inhibitors of NLuc.
Despite the wide substrate specificity of ABCG2, relatively few specific inhibitors, active at submicromolar concentrations, have been reported.
Despite the difficult substrate conditions, T. reesei SVG17 was able to grow on the pre-treated wheat straw and showed efficient and reproducible production of (hemi-) cellulolytic enzymes.
Conversely, when only the catalytic domain-specific Ac-H3K4me3 21mer substrate peptide was tested no perturbations are observed in the protein (Supplementary Figure 7b), despite using saturating concentrations of the substrate (25-fold over protein concentration, ~5 × Km).
