"despite the significant progress" is a grammatically correct and usable part of a sentence in written English.
For example, you could say: "Despite the significant progress our company has made this year, there is still much work to be done to reach our goals."
Despite the significant progress made in the fields of operations research and process systems engineering (Puigjaner, Comp. Chem.
Despite the significant progress made during the last decade, designing materials to control stem cell fate remains challenging.
Despite the significant progress in the field of bone tissue engineering, cell-based products have not yet reached the stage of clinical adoption.
Despite the significant progress in recent years in improving the design and performance of TEHV constructs, viable and functional human implantable TEHV constructs have remained elusive.
Last week, the UN's children's agency, Unicef, said that despite the significant progress made in cutting child deaths since 1990, the MDG to reduce child mortality by two-thirds by 2015 would not be achieved until 2028 without greater effort.
Indeed, despite the significant progress in optical fiber manufacturing, because of residual birefringence or strain the polarization of light remains unpredictable after propagating a few hundred meters in a fiber.
Despite the very significant progress made over the last few months, Bosnia and Albania have not yet been able to complete the necessary reforms requested in the road map to justify the exemption of the visa requirement.
Despite the significant recent progress, some gaps on permafrost distribution still remain as the network for permafrost and active layer monitoring needs further enlargement and better standardization.
Despite the significant innovative progress achieved using nanomaterials to tailor NO release, certain drawbacks still need to be overcome to successfully translate these research innovations into clinical applications.
Despite the significant technological progress in HA technology over the last decade, HA uptake in older adults remains low.
Meanwhile the World Health Organisation (WHO) reported that despite significant progress, the world is unlikely to meet the fourth Millennium Development Goal -- to reduce child mortality by two-thirds from 1990 levels.
