Sentence examples for despite the mutations from inspiring English sources

Despite the mutations and recombinations raise the genetic diversity as evolutionary frorces in a population, the amount of molecular variation observed in this study can not be attributed to only these forces.

All three variant fragments folded and trimerised in vitro, so folding is still thermodynamically favourable, despite the mutations.

Despite the mutations in the fiber and EIA genes, no other genetic differences with the prototype HAdV-14 clearly explain differing disease severity in US outbreaks (13 ).

In this study, the suppressor mutation was identified to be a point mutation in rho encoding the transcription termination factor Rho. Strain RE2 still showed retarded growth despite the mutation rho696.

Despite the mutation changes in cancer samples, matched tumor-normal pairs are still relatively similar in sequence compared to non-matched pairs.

Although our study raises doubts about the contribution of Ser1512 and Ser1568 to the capacity of TRPM7 to undergo autophosphorylation in mammalian cells, it is plausible that an unknown factor in mammalian cells may predispose TRPM7 to undergo massive autophosphorylation despite the mutation of Ser1512 and Ser1568 to alanine.

This strongly suggests that despite the mutation, LMNA p.R435C is able to assemble in its normal region beneath the nuclear membrane.

Despite the mutation, deletion, and multiple alterations, G6pd amplification frequency was higher in ovary cancer (∼9%), cervix cancer (3%), uterine cancer (2%), and breast cancer (2%).

Despite the mutation load, we were able to quantify the multi-hit model of these engineered cancers and highlight a potential new cooperating event with BRAF and p53 mutation through the protein kinase A-cyclic AMP pathway.

Moreover, an overrepresentation of the IGHV3-21 gene has been reported in northern European countries compared to the Mediterranean region, and it has been associated with a worse prognosis despite the mutation status [ 13, 14].

In this cell line, P-1257 inhibits ErbB-3 and IRS-1/p85 IRS-1/p85 formation suggesting that the inacomplexes oformationsuggestingon we observed on thatphosphopepthee treatment could be suffinactivationhibit PI3K activity despite the mutatiof of PIK3CAkt