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Despite the increasing knowledge on the HSC niche, central questions on the relative importance of each cell type, how they cooperate, as well as how HSC localize within the subendosteal niche which regulates their anchorage to osteoblasts require further analyses.
Despite the increasing knowledge of genes that contribute to anther development, the regulatory mechanisms controlling this process are still unclear.
Despite the increasing knowledge about p53 as a transactivator and cellular gatekeeper for cell growth and division, the effects of wild-type p53 (and mutated p53) on drug sensitivity of human tumours including TC are still not clear.
Despite the increasing knowledge on the categorization of SPs and the progress in defining the molecular pathogenesis, data on the real prevalence of SSA/P and TSA among average-risk individuals are very limited.
Recent surveys involving large numbers of ICU healthcare professionals have demonstrated that despite the increasing knowledge of the pathophysiology, risk factors, and outcomes associated with delirium, it is still underdiagnosed, and modifiable risk factors related to its occurrence are frequently neglected [ 8, 9].
Despite the increasing knowledge of the molecular biology of tumours and their interactions with anticancer drugs, less is known about measuring the benefits of treatments in patients in terms of percentages of tumour cells killed and the proportion that is resistant.
Similar(54)
Despite of the increasing knowledge on sociality and tonal sounds the information remains lacking, or scattered, for many species.
Despite the increased knowledge about neurobiological correlates of antisocial behavior in recent years, neurobiological measures do not yet play a significant part in the field of criminology.
Thus, the characterization of Petrosavia plastome demonstrates that despite the increased knowledge on plastid genomes, an important modus of nonphotosynthetic plastomes' evolution, related to genome rearrangements, remained overlooked.
It is of concern that despite the increased knowledge regarding the high prevalence of sleep disorders and their impact on health, 53% of the surveyed course organizers believe that sleep medicine education is a low priority for medical students.
35 By examining gaps in life expectancy rather than mortality rates and by revealing that these gaps have increased over time, the results of this study are significant in that they show that outcomes for people with mental illness have worsened since the 1990s despite increasing knowledge about the impacts of such illness.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com