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Despite the increased understanding based on advancements on genomic level, the possible implications for treatment remain elusive.
Despite the increased understanding of how accidents occur in the chemical process industry, today's safety measures and indicators do not prevent these accidents from occurring.
Despite the increased understanding of this new invasive syndrome [ 4], only earlier diagnosis and effective treatment can minimize the occurrence of sequelae and improve clinical outcomes.
Despite the increased understanding of how tumor cells acquire resistance to platinum-based compounds, there are still limited second-line treatment options/strategies for patients who relapse and/or are refractory to conventional chemotherapeutics.
Compared to other cancers, such as breast and ovarian cancers, there is no biological or genetic classifier for PDAC tumours, despite the increased understanding of genetic heterogeneity among PDAC tumours [ 6, 11, 12].
However, despite the increased understanding of genetic causes and direct detection of mutations in the LDLR, APOB, PCSK9 and LDLRAP genes, the vast majority of diagnoses still rely on the more historical clinical criteria.
Similar(53)
Despite intensive investigation of cartilage repair strategies and the increased understanding of the cellular mechanisms involved, many issues remain to be resolved.
Despite the increasing understanding of the immune responses behind the formation and maintenance of the granulomatous process in sarcoidosis, its etiology remained elusive.
Despite the increasing understanding of female reproduction, the molecular diagnosis of primary ovarian insufficiency (POI) is seldom obtained.
Despite the increasing understanding of female reproduction, defined causes or mechanisms resulting in primary ovarian insufficiency remain largely unknown [ 7].
Despite the increasing understanding of the biological processes of cancer development, there is still a strong need for novel and effective pharmacological strategies for intervention with this disease [ 2].
More suggestions(16)
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CEO of Professional Science Editing for Scientists @ prosciediting.com