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It deserves mention, however, that despite the enhancing effect of ROS on UPS activity observed in this and other studies, impaired UPS function has also been correlated with ROS.
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Despite the significantly enhanced cytotoxicity, the mode of cell death was not changed as CsA completely abrogated cell death.
In contrast, at higher PDT doses and despite the progressively enhanced immediate cell killing, the recovery of FSA was reduced relative to DAMPs.
Despite the recent discoveries enhancing the available options for cancer treatment, relapse from this disease remains a major hurdle in clinics.
Despite enhancing the activity of the unmodified base oxides, the addition of low levels of Pt has been demonstrated to poison the activity of "superacidic" zirconias.
Cotten, S. W. et al. Genetic myostatin decrease in the golden retriever muscular dystrophy model does not significantly affect the ubiquitin proteasome system despite enhancing the severity of disease.
Despite enhancing the drug-drug interaction knowledge database, the alert override rate of this system was very high.
Despite enhancing the induction of apoptosis by etoposide (Supplementary Figure S3B), the drug inhibited lipid droplet formation (Supplementary Figure S3C), decreased the incorporation of C-acetate into TAG and increased C incorporation into FFA (Supplementary Figures S3D and S3E).
Despite this clarity, enhancing the energy efficiency introduce significant challenge toward process operation.
The osteogenic differentiation of MSCs was suppressed on pure collagen substrate alone, despite collagen greatly enhancing the MSC adhesion and proliferation.
Despite attempts in enhancing the efficacy of conditioning regimens and graft versus leukemia (GvL) effects, disease relapse still commonly occurs.
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