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Despite the altered position of slow and fast fibres, Engrailed expression is similar to that in wild type embryos (Fig. 3G,L).
Despite the altered orientations of the nucleotide binding pockets, the ADP α-phosphate is near the peptide-binding site.
Since a physiological response may proceed normally despite the altered regulation of certain genes, we also analyzed the expression of several marker genes 4 hours after hCG treatment in knockout and wild-type ovaries (Fig. 6).
Despite the altered chromatin structure in mutant early blastocysts, Cdx2 expression remained restricted to the TE and was not detected in EPI cells (data not shown), which is consistent with previous reports [48].
One explanation for the unaltered myelin formation despite the altered level of MOG, MAG and MBP might be that the extent of reduction, which is subtle compared with the large reductions observed in the mice without the PGKneo cassette [18], was not enough to induce a significant change in the myelin formation during development.
Despite the altered positioning, several potential favorable interactions are suggested.
Similar(48)
Despite the phenotypes of the altered immune response in HBV chronic carriers in the different clinical stages have been extensively characterized, the mechanism of HBV infection to induce the dysfunctional immune responses leading to a persistent infection remains elusive.
Despite the low overlap between the altered gene sets for each cell line, the network analysis demonstrated that their cancer-related functionality was cooperative, which we detected at both the pathway and global-network level.
The altered mitochondrial function occurred despite well-maintained total and microcirculatory hepatic blood flow.
However, despite altered MtDNA levels in DC and DN, we did not see any significant alterations in mRNAs levels of mitochondrial encoded subunits (Fig. 1B D) or in most nuclear encoded mitochondrial mRNAs (Fig. 1F J), suggesting that the altered MtDNA levels are not functional.
It proved to be efficient at neutralizing sphingomyelinase and hemolytic activities of the crude venom despite the slightly altered binding kinetic constants and the limited stability of the dimeric configuration.
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