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Introduction Despite substantial improvements in the management of multiple myeloma, renal failure remains an important burden which tremendously impairs prognosis.
However, despite substantial improvements in the properties, the lack of reliable joining methods has restricted their full potential.
Despite substantial improvements in objective health measures, there has not been a commensurate increase in assessments of subjective health.
Despite substantial improvements in the treatment of head and neck cancer (HNC) over the last two decades, overall survival rates remain unsatisfactory.
Despite substantial improvements in some health indicators in the past decade, India contributes disproportionately to the global burden of disease, with health indicators that compare unfavourably with other middle-income countries and India's regional neighbours.
Despite substantial improvements in intra- and postoperative management of extended hemihepatectomy as the curative option for treatment of central liver tumors, the high morbidity and mortality rates accompanying the procedure still represent major obstacles.
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Despite substantial improvement in understanding the pathophysiologic features of GCA, some mechanisms still remain unclear, especially in relation to vascular remodelling.
Despite substantial improvement in PUB management, the mortality in cirrhotic patients remains high, especially among patients with advanced liver cirrhosis [ 32, 33].
However, despite these substantial improvements in diagnostic procedures, a significant number of cancer patients will not have the primary site of their cancer discovered.
In addition, substantial improvements in risk reclassification may be apparent despite limited increases in the c statistic.
While there were substantial improvements in poverty reduction and education, other goals showed patchier progress.
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