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Despite robust evidence to guide clinical care, most patients with diabetes do not meet all goals of risk factor control.
Consistent evidence of an influence of maternal dietary intake during pregnancy on infant body size and composition in human populations is lacking, despite robust evidence in animal models.
Despite robust evidence of neurocognitive dysfunction in psychotic patients, the degree of similarity in cognitive architecture across psychotic disorders and among their respective first-degree relatives is not well delineated.
Despite robust evidence supporting the immediate transfer of severely injured patients, over one-half of the cohort transferred to UPMC Presbyterian received a CT scan prior to their transfer.
Despite robust evidence from a landmark trial and systematic review of the effectiveness of magnesium sulphate for the treatment of pre-eclampsia, the drug is still not available in some countries and its availability varies in many others.
However, we suspect that under-representation of heavy drinkers in Scotland explains our finding that Scottish consumption levels are lower and abstention rates higher despite robust evidence to the contrary.
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In the context of persistent inadequate prescribing despite robust evidence-based guidelines, and poor adherence in those receiving multiple monotherapy, our data suggest that the polypill offers a cost-effective approach to improving outcomes for a substantial proportion of the UK population.
Despite such robust evidence of the benefits of methadone maintenance therapy, it remains, for some, a highly controversial practice.
Despite the robust evidence base demonstrating the efficacy of ECT, the number of patients being treated with it has fallen dramatically in recent decades.
Despite the robust evidence of a triangular relationship among high PTHLH secretion, hypercalcemia, and patient poor prognosis, the relevance of PTHLH expression to the survival of patients with RCC was not clear in the previous analyses.
13 Despite this robust evidence base, the reality for most people affected by mental disorders has been an uncaring health system that does little to respond to their needs, leading to estimates that up to three of four affected persons in LAMICs do not receive the treatments known to work.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com