Sentence examples for despite our substantial from inspiring English sources

Despite our substantial efforts on the IP front, you have agreed to schedule only two meetings since July and during those meetings you have been unwilling to engage with us on any productive proposals that adequately recognize the changed market dynamics in your markets and the decline in value of your patent portfolio in the period since the IP license was last renewed.

While we have no such information for other correlates such as longevity, number of broods per life, offspring survival, etc., our current limited evidence suggests that P. formosa experiences only little or no genomic decay despite our predictions of substantial deleterious mutation accumulation.

In our country, despite a substantial increase in the assisted delivery rate to 97%, the maternal mortality rate remains high.

This is despite a substantial increase in our understanding of GPCR pharmacology that has provided an array of ligands that target both orthosteric and allosteric sites as well as ligands that show stimulus bias.

Despite these substantial population shifts, our findings clearly showed that effects of RS and their magnitude varied among individuals.

It is disappointing that despite the substantial advances in our understanding of the molecular basis of disease, there is a paucity of approved biomarkers.

Taken together, despite the substantial advance in our understanding of the role of this small β-AR amplifier in the heart, it is still unclear whether I-1 is a promising therapeutic target in heart failure and if yes, whether its activity/amount should be increased or decreased.

Despite being substantial, the outbreak costs in our study are underestimated.

Their statement continued: "Despite receiving a substantial bid for our Moroccan international, we rebuffed all approaches.

Clinical outcome in ARDS remains poor despite substantial advances in our understanding of the biology of this syndrome [ 2].

Despite substantial advances in our understanding of EDCs, uncertainties and knowledge gaps still exist that are too important to ignore.