Despite major government subsidies, Mr. Halstead shuns new regulations.
Unlike most prime-time fare "Barney Miller" flourished despite major cast upheavals.
Despite major advances in psychiatric diagnosis and treatment, fewer and fewer Americans have adequate coverage for appropriate care.
And despite major advances in console hardware, top-end PC graphics remain the gold standard for visual fidelity and impact.
Despite major scandals, the Department for Business, Innovation and Skills has never prosecuted any UK auditing firm for negligence.
But despite major shifts in sociological contexts, the ban against homosexuality was rigidly enforced throughout the centuries.
Despite major media coverage of the discovery, many people still don't understand its momentous meaning and significance.
Despite major advances in drug development, effective cardiovascular therapies and suitable cardiovascular biomarkers remain limited.
This is despite major ice sheets reoccupying the region during cold intervals since the mid-Pleistocene.
Despite major developments in botics, the user's affective responses towards bots have frequently been neglected.
Despite major advances in cancer chemotherapeutics and immunotherapy, the success in treating metastatic melanoma remains poor.
