We have previously shown that Mena, despite its localization to the actin tail, has no role in S. flexneri actin-based motility.
Despite the localization of the chimeric dengue antigen to the insoluble fraction of induced E. coli cells, it was found to be biotinylated in vivo.
Finally, tests of samples with printed architecture localized to the gage section revealed an effect in which fatigue performance appeared to drastically improve despite the localization of strain.
Despite the localization of the conserved catalytic triad to the core domain, levulinic acid is bound largely within the region of the active site defined by the cap domain, suggesting a key role for this divergent substructure in mediating product release.
Modelling carried out to replicate GNP uptake equal to 1% mass in the cytosol demonstrated dose enhancement in both the nucleus and mitochondria, despite cytosol localization.
More importantly, microscopy measurements demonstrated, for the first time, that cell killing is enhanced despite the localization of the radio-enhancing agents in the cytoplasm, and not in the nucleus, of the cells (see Fig. 2a).
Despite similar localization, NMMIIA, NMMIIB and NMMIIC do not form heterodimers in intestinal epithelial cells (Figure 2B), which is a critical prerequisite for functional diversity of the NMMII heavy chains.
Despite the localization at the interchromatid domain, RAD21 appeared concentrated onto T-shaped structures at the centromeres of all autosomes (Fig. 5G) and the centromere of the X chromosome (Fig. 5K).
Despite nuclear localization and catalytic activity in vitro, the mutant protein was biologically inactive in vivo leading to premature senescence with activation of the classical telomere-related DNA damage response (DDR), when expressed in primary cells.
Therefore, the proximal tract of the ascending dendrite unlikely forms synaptic contacts with the granule cell axons, despite its localization in the granular layer, while the distal tract is extensively bordered by PFs.
RabX1 and RabX2, two members of the trypanosome Rab subfamily, were shown to have no major detectable role in intracellular transport, despite the localization of each gene product to highly specific endomembrane compartments.
