Exact(5)
Despite its interaction with the nearby islands, Utor continued to strengthen without much impediment and reached typhoon strength in the Visayan Sea at 12 00 UTC that day.
Despite its interaction with the Sec61 translocon, the XBP1u nascent chain inefficiently inserts into the ER membrane due to its weak hydrophobic region.
Multivariate analysis confirmed that Aurora B overexpression was an independent poor prognostic factor, despite its interaction with Aurora A overexpression and mutations of p53 and β- catenin.
Transfection of the Y129C single and double mutant MC2R into CHO cells stably transfected with MRAP revealed that the Y129C mutant fails to reach the cell surface, despite its interaction with MRAP.
Interestingly, M11L binding to Bak and Bax is required for its survival promoting activity, yet despite its interaction with Bim, the latter is not involved in the anti-apoptotic function of M11L (Kvansakul et al., 2007).
Similar(55)
In addition, alanine point mutants of prolines 2 and 4 (indicated in bold face) of the PPPRPPK motif had no obvious effect on the Vav/Themis2 interaction despite inhibiting its interaction with Grb2 (Fig. 3b, discussed below) arguing against this motif as a Vav binding site.
Despite favorable upper-level conditions, its interaction with land combined with the weakening of a ridge to the north left the storm's center distorted.
However despite the critical nature of its interaction with macrophages, few anti-macrophage factors have been characterized to date.
Indeed the lack of conservation of residues in eIF3b which are involved in its interaction with eIF3i (despite a conservation of the eIF3b binding residues in eIF3i) might indicate significant divergence in this interaction in different organisms.
Moreover, the lack of interaction between unliganded AR and DICER, despite their co-existence in the cytoplasm, suggests that conformational changes in AR lead to its interaction with DICER.
Despite the weakness of its interactions, scientists have a real chance in the coming decade of identifying and deducing the nature of dark matter.
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