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Preclinical testing of new vaccine candidates is usually done in naïve animals, despite intended use in the human population with its varied immune history including responses to previous vaccinations.
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Despite intending to help workers and employers, the government managed to make both unhappy.
Many settled here permanently despite intending to return home, because the value of their contribution was recognised.
Despite intending to release a follow-up in the 1960s, Smith was injured in an accident leading to a follow-up never eventuating.
Despite intending to accord the other "Germanics" of Europe a racially superior status alongside the Germans themselves in an anticipated post-war racio-political order, the Nazis did not however consider granting the subject populations of these countries any national rights of their own.
Despite intending to recruit patients, GPs reported forgetting to approach patients to participate, and did not perceive that patients had neither a strong interest nor disinterest in participating.
Despite subsidies intended to help the poor, prices for staples, such as milk, bread, rice, yogurt and vegetables, have at least doubled since the beginning of the year.
Retail sales were also sluggish and frequently below expectations during the survey period, despite discounts intended to lure shoppers to stores.
Others, despite rules intended to forbid the practice, indicate how they would decide on issues like the death penalty or abortion.
Despite laws intended to protect the mentally ill from abuse, many facilities operate under the radar screen, and their abusive practices are not detected by overworked regulators until a tragedy occurs.
In a briefing with Spanish-speaking reporters last month, President Obama acknowledged that immigration enforcement was splitting up families despite laws intended to keep them together.
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