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Despite increased knowledge of hamstring muscle injuries, the incidence has not diminished.
Despite increased knowledge of pathogenesis and improved treatment regimens, LN remains a main cause of morbidity among patients with SLE [ 2].
Despite increased knowledge of the risk factors, the proportions of PTB and LBW are increasing in developed countries (e.g., from 10.6% and 5.9% in 1990 to 12.2% and 6.4% in 2009 in the United States, respectively) [ 4].
Septic shock is the major cause of death in the ICU, and despite increased knowledge of the pathogenesis of sepsis and the creation of 'bundles' of care by the international consortium 'Surviving Sepsis Campaign', the septic shock mortality rate remains high [ 28- 30].
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Despite increased knowledge on the pathophysiological process, many aspects remain rather unclear, especially concerning IBD.
Despite increasing knowledge of turbidity current triggers, the down-canyon variability in turbidity current frequency within most canyon systems is not well constrained.
Despite increasing knowledge of the genetics and biochemistry of NP-C, convenient, easily applied diagnostic methods are lacking.
Despite increasing knowledge of replication and packaging of HEV in somatic cells, an efficient cell culture method is currently not available (38, 39 ).
Despite increasing knowledge of the closeness of human and animal destiny, the "mutual obligation" so clearly defined by Charron is slow to advance.
Despite increasing knowledge of attention deficit hyperactivity disorder (ADHD) across the life span, there is still little research on adults' own experiences of being diagnosed with ADHD.
Despite increasing knowledge of the uraemic syndrome, both morbidity and mortality remain unacceptably high in patients with end-stage kidney disease (ESKD) [ 3].
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