Treatment-related toxicity, together with the 10 to 30% of patients who do not respond to traditional immunosuppressive agents and pursue a refractory course and the 50% of patients who relapse within 5 years despite continued immunosuppression, has shifted the focus of treatment for AAV [ 12].
What's more, such is the power of Rose that, despite resistance, that look has shifted from Balmain to current season Topshop, H&M and Zara.
Despite this, the focus has shifted from osteoporosis as a disease of trabecular bone resulting in spinal fractures, to a state of risk of fracture, with a focus on non-vertebral, substantially cortical bone fractures that occur in a fall.
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One senior administration official, who asked not to be named, said a major goal was to remind people that Ukraine was not forgotten despite the fact that attention has shifted toward Russia's involvement in Syria.
The momentum had shifted again and, despite the one-man advantage, Arsenal did not put Schmeichel under any concerted pressure during the first period of extra time.
She attributed Republicans' poor performance in the poll to a soft line on immigration and an eagerness to use the issue to cultivate Latino votes, despite the fact that the party has shifted to the right on immigration in recent months.
Nor, despite the conniptions about race, will the party have shifted decisively left or right.
Despite Sturgeon's insistence that the Brexit vote had shifted Scottish opinion, a YouGov poll for the Times Scotland on Friday suggested the figure in favour of independence had barely shifted over the past two years, despite the June referendum.
