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"despite extensive research" is a correct and usable phrase in written English.
You can use this phrase when you want to emphasize that a particular outcome happened despite significant work having been done to try to prevent it. For example: "Despite extensive research by the development team, the product still failed to meet customer expectations."
Exact(60)
Despite extensive research, the underlying concept for peak multiplicity is not yet clearly understood.
However, despite extensive research, the establishment of proper relationships has proved difficult.
Despite extensive research, DNA damage repair and signaling are not fully understood.
Despite extensive research into the disease etiology, its underlying molecular processes remain unknown.
Despite extensive research in this direction, finding out the most appropriate weights is still very challenging.
Despite extensive research efforts, drug addiction persists as a largely unmet medical need.
Despite extensive research, however, it has proved difficult to demonstrate in nonhuman animals.
Despite extensive research, wear of the bearing surfaces, particularly metal metal hips, remains a major problem.
Yet, despite extensive research many aspects of fracture initiation and propagation in such materials remain unclear.
The severity is unpredictable, and, despite extensive research, the etiology remains unknown.
Despite extensive research, no reliable blood tests currently exist for the diagnosis of endometriosis.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com