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Despite crucial, TCR/pMHC interaction is generally insufficient for the productive T cell activation, for which accessory (costimulatory) receptor/ligand interactions, typified by CD28/B7-1 CD28/B7-1ocyte function andociated antigen-1 (lymphocyteercellular adhesion molecule-1 (ICAM-1), are required [2], [3].
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Yet, despite these crucial needs, adolescents are not well catered for.
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Despite its crucial role in managing the earth's climate, however, scientists know surprisingly little about the Arctic compared with the world's other oceans.
The following fascinating footage, from 1952, suggests why, despite the crucial importance of their collaborations, the two didn't play together all that often.
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When "The Hour" had its premiere here on BBC2 last month (it has its BBC America premiere Wednesday at 10 p.m ., "Mad Men" comparisons abounded despite some crucial differences.
In an joint article ahead of the event, they said the twin issues were rarely discussed in top-level political talks despite being "crucial for the growth and competitiveness Europe so desperately needs".
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