It has proved difficult, however, to distinguish between these processes on the basis of direct field observations, despite considerable effort.
Charlotte, N.C., has attracted dozens of restaurants to its downtown but, despite considerable effort, virtually no retail establishments.
Despite considerable effort to reduce low back pain (LBP), approximately 60% of patients have recurrence after their first episode.
Mr. Grasso said an injunction would augment existing enforcement initiatives against prostitution that despite considerable effort have not significantly dented the problem in Queens Plaza.
But even Enbrel is "not meeting expectations, despite considerable effort," George Morrow, an executive vice president at Amgen, told analysts recently.
Despite considerable effort over a century and the benefit of remarkable technical advances in the past few decades, we are still far from understanding mammalian cerebral neocortex.
However, typical of protein-protein interactions, traditional unbiased approaches to ligand discovery did not produce viable hits against this target, despite considerable effort and a multitude of approaches.
The paper then describes regulatory interventions in this area and concludes that, despite considerable effort and some local success, none have materially curbed the expansion—or the adverse effects of STSDC products nationally.
When stars like Michael Jordan and Wayne Gretzky captured our imaginations, their respective sports already had big, solid bases of fans, something that despite considerable effort by many, soccer has yet to attract in America.
Despite strong demand for information to support the sustainable use of Australia's natural resources and conserve environmental values and despite considerable effort and investment, nation-wide environmental data collection and analysis remains a substantially unmet challenge.
Sure enough, the text fails to coalesce into a compelling narrative despite considerable effort by the British director Robert Shaw and his three performers to chisel out specific personalities (Francis Benhamou's battle-scarred benevolence, Angela Church's wry melancholy, Kina Bermudez's peevish grief).
